Nom du produit:2-(trans-4-Hydroxycyclohexyl)isoindoline-1,3-dione
IUPAC Name:2-[(1r,4r)-4-hydroxycyclohexyl]-2,3-dihydro-1H-isoindole-1,3-dione
- CAS:99337-98-1
- Formule moléculaire:C14H15NO3
- Pureté:95%+
- Numéro de catalogue:CM148256
- Poids moléculaire:245.28
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:99337-98-1
- Formule moléculaire:C14H15NO3
- Point de fusion:-
- Code SMILES:O=C1N([C@H]2CC[C@H](O)CC2)C(C3=C1C=CC=C3)=O
- Densité:
- Numéro de catalogue:CM148256
- Poids moléculaire:245.28
- Point d'ébullition:410°C at 760 mmHg
- N° Mdl:
- Stockage:Store at 2-8°C.
Category Infos
- Cyclohexanes
- Cyclohexane is an organic compound with a chemical formula C6H12. It is a colorless liquid with a pungent odor, insoluble in water, and soluble in most organic solvents such as ethanol, ether, benzene, and acetone. Cyclohexyl fragments are a common structure in both natural and synthetic drugs. It can be used as both core structure and part of achiral side chain.
Column Infos
- Cadisegliatin
- vTv Therapeutics announces FDA submission for first phase 3 study of Cadisegliatin in patients with type 1 diabetes. Cadisegliatin (TTP399) is developed as an adjunctive therapy to insulin for the treatment of type 1 diabetes, and the phase 3 trial evaluates its safety and efficacy.
Glucokinase (GK) is mainly concentrated in liver cells, and involved in the regulation of glucose metabolism. Cadisegliatin (TTP399) is a liver-selective glucosekinase activator with a mechanism of action different from that of antidiabetic drugs. It binds to the allosteric site of GK and restores innate glucose-regulating capacity of the liver, not disrupting the interaction between GK and GKRP. Cadisegliatin previously received a Breakthrough Therapy designation from the U.S. FDA.