Nom du produit:N-(3-{6-methoxyimidazo[1,2-b]pyridazin-2-yl}phenyl)-2,3-dihydro-1,4-benzodioxine-6-sulfonamide

IUPAC Name:N-(3-{6-methoxyimidazo[1,2-b]pyridazin-2-yl}phenyl)-2,3-dihydro-1,4-benzodioxine-6-sulfonamide

CAS:946323-73-5
Formule moléculaire:C21H18N4O5S
Pureté:95%+
Numéro de catalogue:CM645376
Poids moléculaire:438.46

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Détails du produit

N° CAS:946323-73-5
Formule moléculaire:C21H18N4O5S
Point de fusion:-
Code SMILES:COC1=NN2C=C(N=C2C=C1)C1=CC=CC(NS(=O)(=O)C2=CC=C3OCCOC3=C2)=C1
Densité:
Numéro de catalogue:CM645376
Poids moléculaire:438.46
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

Benzodioxanes
Benzodioxanes are a class of isomeric compounds with the molecular formula C8H8O2. The three isomers of benzodioxane are 1,2-benzodioxane, 1,3-benzodioxane and 1,4-benzodioxane. 1,4-Benzodioxane has long been a versatile template widely used to design molecules with diverse biological activities. Its use spans past decades in medicinal chemistry to today, involving many drug discovery strategies, not excluding the most advanced ones. 1,4-Benzodioxane derivatives have been described as agonists and antagonists of nicotinic, alpha-adrenergic and 5-HT receptor subtypes. 1,4-Benzodioxane derivatives have been also reported as antitumor and antibacterial agents.
Imidazopyridazines
Potent IRAK-4 inhibitors have been reported by several groups including some structurally related benzimidazoles as well as alternative fused heterocycles such as the imidazopyridine and imidazopyridazine. Such compounds are reported to have IRAK-1 and IRAK-4 activity with varying degrees of selectivity.