cas 941000-16-4|| where to buy 3-(azepane-1-sulfonyl)-N-(isoquinolin-5-yl)-4-methylbenzamide

Nom du produit:3-(azepane-1-sulfonyl)-N-(isoquinolin-5-yl)-4-methylbenzamide

IUPAC Name:3-(azepane-1-sulfonyl)-N-(isoquinolin-5-yl)-4-methylbenzamide

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: N° CAS:941000-16-4; Formule moléculaire:C23H25N3O3S; Point de fusion:-; Code SMILES:CC1=C(C=C(C=C1)C(=O)NC1=CC=CC2=CN=CC=C12)S(=O)(=O)N1CCCCCC1; Densité:

: Numéro de catalogue:CM856506; Poids moléculaire:423.53; Point d'ébullition:; N° Mdl:; Stockage:

: Isoquinolines; Compared to quinolines, isoquinolines are also prominent structural motifs present in many biologically significant natural and synthetic compounds. Some well-known isoquinoline alkaloids include the anticancer and anticonvulsant berberine, the vasodilator and antispasmodic drugs papaverine and emetine. In addition to naturally occurring isoquinolines, synthetic analogs have also shown significant biological activity.

: Azepanes; The use of azepane as a scaffold for drug discovery remains of interest. The azepane linker is the key to efficient activity. A number of seven-membered ring derivatives have been prepared or investigated for their potential or actual pharmacological properties. Examples include azaalkane derivatives as PKB (protein kinase B) inhibitors.