Nom du produit:6-Cyclopropyl-1-(4-methoxyphenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

IUPAC Name:6-cyclopropyl-1-(4-methoxyphenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

CAS:937600-18-5
Formule moléculaire:C18H17N3O3
Pureté:95%+
Numéro de catalogue:CM271976
Poids moléculaire:323.35

Unité d'emballage Stock disponible Prix($) Quantité
CM271976-1g 1-2 Weeks ǙIJƈ
CM271976-5g 1-2 Weeks ȃƥƈ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:937600-18-5
Formule moléculaire:C18H17N3O3
Point de fusion:-
Code SMILES:O=C(C1=C2C(N(C3=CC=C(OC)C=C3)N=C2C)=NC(C4CC4)=C1)O
Densité:
Numéro de catalogue:CM271976
Poids moléculaire:323.35
Point d'ébullition:
N° Mdl:MFCD08556283
Stockage:

Category Infos

Pyrazolopyridines
Over the past few years, many pyrazole fused-ring systems, especially with applications in medicinal chemistry, have been published. These include general structures such as pyrazoline, pyrazoline, pyrazoquinoline, pyrazoloisoquinoline, pyrazoline, pyrazolopyrazine, pyrazolopyrazine, pyranopyrazole, pyrano Pyrazoles, pyrazolotriazines and pyrazole fused phosphorus rings.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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