Nom du produit:4-chloro-2-(methylthio)-5-(trifluoromethyl)pyrimidine
IUPAC Name:4-chloro-2-(methylsulfanyl)-5-(trifluoromethyl)pyrimidine
- CAS：919116-36-2
- Formule moléculaire：C6H4ClF3N2S
- Pureté：95%
- Numéro de catalogue：CM128233
- Poids moléculaire：228.62
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:919116-36-2
- Formule moléculaire:C6H4ClF3N2S
- Point de fusion:-
- Code SMILES:FC(C1=CN=C(SC)N=C1Cl)(F)F
- Densité:
- Numéro de catalogue:CM128233
- Poids moléculaire:228.62
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- Pyrimidines
- Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Column Infos
- DCC-3116
- DCC-3116 is an investigational, orally administered, potent, and highly selective switch-control inhibitor of the ULK kinase. DCC-3116 is designed to inhibit autophagy, a key tumor survival mechanism in cancer cells, by inhibiting the ULK1/2 kinases, which have been shown to be the initiating factors that activate autophagy. DCC-3116 in combination with RAS/MAP kinase signaling pathway inhibition has the potential to change the treatment of RAS/RAF cancers.
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