cas 904899-19-0|| where to buy (E)-N-{2-[2-(1H-indazol-3-yl)vinyl]-5-(piperazin-1-ylmethyl)phenyl}-3-methylthiophene-2-carboxamide

Nom du produit:(E)-N-{2-[2-(1H-indazol-3-yl)vinyl]-5-(piperazin-1-ylmethyl)phenyl}-3-methylthiophene-2-carboxamide

IUPAC Name:N-{2-[(1E)-2-(1H-indazol-3-yl)ethenyl]-5-[(piperazin-1-yl)methyl]phenyl}-3-methylthiophene-2-carboxamide

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: N° CAS:904899-19-0; Formule moléculaire:C26H27N5OS; Point de fusion:-; Code SMILES:CC1=C(SC=C1)C(=O)NC1=C(\C=C\C2=NNC3=CC=CC=C23)C=CC(CN2CCNCC2)=C1; Densité:

: Numéro de catalogue:CM1013659; Poids moléculaire:457.6; Point d'ébullition:; N° Mdl:; Stockage:

: Thiophenes; Thiophene is a five-membered heterocyclic compound containing a sulfur heteroatom with the molecular formula C4H4S. Thiophene is aromatic and is very similar to benzene; electrophilic substitution reaction is easier than benzene, and it is mainly substituted at the 2-position. Thiophene ring system has certain stability to oxidant.

: Piperazines; Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.

: Indazoles; Indazoles are a class of organic heterocyclic compounds, also known as 1,2-diazaindene and benzopyrazole. Indazole is a good bioisomer of phenol, which is more lipophilic than phenol and less prone to phase I and II metabolism. Indazole derivatives have a wide range of biological activities, and it has been confirmed that indazole compounds have anti-tumor, analgesic, anti-inflammatory and other drug activities. Anticancer is the most important application field of indazole drugs. Renal cell carcinoma, solid tumor, nausea and vomiting caused by chemotherapy and leukemia are the main indications of this structural backbone drug.