Nom du produit:4-Cyclopropyl-6,7-dimethyl-1,4-dihydroquinazoline-8-carbonitrile
IUPAC Name:4-cyclopropyl-6,7-dimethyl-1,4-dihydroquinazoline-8-carbonitrile
- CAS：89638-32-4
- Formule moléculaire：C14H15N3
- Pureté：95%+
- Numéro de catalogue：CM218254
- Poids moléculaire：225.3
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Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:89638-32-4
- Formule moléculaire:C14H15N3
- Point de fusion:-
- Code SMILES:N#CC1=C(C)C(C)=CC2=C1NC=NC2C3CC3
- Densité:
- Numéro de catalogue:CM218254
- Poids moléculaire:225.3
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- Quinazolines
- Quinazolines belong to heterocyclic chemistry, also known as 1,3-naphthalenes. The backbone consists of two six-membered aromatic rings fused to each other, with two nitrogen atoms at positions 1 and 3 on the backbone. The presence of these two nitrogen atoms in quinazoline increases its importance in pharmaceutical and biological reactions. Quinazolines and their derivatives are among the most important heterocyclic compounds due to their diverse chemical reactivity and important range of biological activities.
- Cyclopropanes
- Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.
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