Nom du produit:4-Aminophenylboronic acid
IUPAC Name:(4-aminophenyl)boronic acid
- CAS:89415-43-0
- Formule moléculaire:C6H8BNO2
- Pureté:95%+
- Numéro de catalogue:CM143205
- Poids moléculaire:136.95
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:89415-43-0
- Formule moléculaire:C6H8BNO2
- Point de fusion:-
- Code SMILES:OB(C1=CC=C(N)C=C1)O
- Densité:
- Numéro de catalogue:CM143205
- Poids moléculaire:136.95
- Point d'ébullition:
- N° Mdl:MFCD01074656
- Stockage:
Category Infos
- Boronic Acids and Esters
- Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Column Infos
- BMF-219
- Biomea Fusion’s BMF-219 demonstrates promising early signs of clinical activity, with its ability to achieve durable and sustained complete responses (CRs) and minimal residual disease negativity (MRD-neg) in patients with acute myeloid leukemia (AML). Biomea Fusion recently presents this First Complete Responder from Ongoing Phase I Study at the 2023 ASH.
BMF-219 is the first and only covalent menin inhibitor in clinical development for AML, ALL, DLBCL, MM and CLL. Additionally, BMF-219 is being explored for its potential to regenerate insulin-producing beta cells as a treatment of type 1 diabetes.