Nom du produit:4-bromo-2-chloropyrimidine

IUPAC Name:4-bromo-2-chloropyrimidine

CAS:885702-34-1
Formule moléculaire:C4H2BrClN2
Pureté:98%
Numéro de catalogue:CM124232
Poids moléculaire:193.43

Unité d'emballage Stock disponible Prix($) Quantité
CM124232-5g in stock ǫȯǑ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:885702-34-1
Formule moléculaire:C4H2BrClN2
Point de fusion:-
Code SMILES:ClC1=NC=CC(Br)=N1
Densité:
Numéro de catalogue:CM124232
Poids moléculaire:193.43
Point d'ébullition:291.552°C at 760 mmHg
N° Mdl:MFCD08272196
Stockage:Keep in inert atmosphere, store in freezer, under -20°C.

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

Column Infos

Encorafenib plus Binimetinib
U.S. FDA approved Pfizer's BRAFTOVI® (Encorafenib) + MEKTOVI® (Binimetinib) for the treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) with a BRAF V600E mutation. The FDA's approval is based on data from the ongoing Phase 2 PHAROS clinical trial. Encorafenib is an oral small molecule BRAF kinase inhibitor, and Binimetinib is an oral small molecule MEK inhibitor targeting key proteins in the MAPK signaling pathway (RAS-RAF-MEK-ERK).
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.