Nom du produit:2-Ethylbutyric Acid

IUPAC Name:2-ethylbutanoic acid

CAS:88-09-5
Formule moléculaire:C6H12O2
Pureté:95%+
Numéro de catalogue:CM394240
Poids moléculaire:116.16

Unité d'emballage Stock disponible Prix($) Quantité
CM394240-500mg in stock şȋ
CM394240-1g in stock œş

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:88-09-5
Formule moléculaire:C6H12O2
Point de fusion:-
Code SMILES:CCC(CC)C(O)=O
Densité:
Numéro de catalogue:CM394240
Poids moléculaire:116.16
Point d'ébullition:
N° Mdl:
Stockage:

Column Infos

KB-0742
Kronos Bio announces the first patient dosed in an expansion cohort with KB-0742 at a dose of 80mg given on a four-days-on, three-days-off schedule. This expansion cohort is enrolling platinum-resistant patients with high-grade serous ovarian cancer (HGSOC). Many cancers exhibit transcriptional deregulation, often characterized by gene amplifications of MYC family oncogene. Targeting the transcription elongation cofactor, cyclin-dependent kinase 9 (CDK9) has emerged as a therapeutic strategy to disrupt MYC oncogenic activity.
KB-0742 is an oral highly selective CDK9 inhibitor designed for the treatment of patients with MYC-amplified and other transcriptionally addicted relapsed or refractory solid tumors, including ovarian, lung, and triple-negative breast cancers.