Nom du produit:1-Cyclopropyl-5-oxo-pyrrolidine-3-carboxylic acid

IUPAC Name:1-cyclopropyl-5-oxopyrrolidine-3-carboxylic acid

CAS:876716-43-7
Formule moléculaire:C8H11NO3
Pureté:95%
Numéro de catalogue:CM196846
Poids moléculaire:169.18

Unité d'emballage Stock disponible Prix($) Quantité
CM196846-5g 3-4 Weeks ƚħħ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:876716-43-7
Formule moléculaire:C8H11NO3
Point de fusion:-
Code SMILES:O=C(C(C1)CN(C2CC2)C1=O)O
Densité:
Numéro de catalogue:CM196846
Poids moléculaire:169.18
Point d'ébullition:401.2°C at 760 mmHg
N° Mdl:MFCD06660782
Stockage:Store at 2-8°C.

Category Infos

Amino Acids and Peptides
Amino acids are organic compounds containing a basic amino group and an acidic carboxyl group. Because amino acids contain both amino and carboxyl groups, they can be polymerized in an end-to-end manner, removing a molecule of water to form a covalent amide bond or peptide bond. Many amino acids are linked together end to end to form a polypeptide. Amino acids and peptides are important components in the fields of medicine and life sciences.
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Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.