Nom du produit:4-chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine
IUPAC Name:4-chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine
- CAS:876343-10-1
- Formule moléculaire:C6H3ClIN3
- Pureté:95%+
- Numéro de catalogue:CM104043
- Poids moléculaire:279.47
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:876343-10-1
- Formule moléculaire:C6H3ClIN3
- Point de fusion:-
- Code SMILES:ClC1=C2C=C(I)NC2=NC=N1
- Densité:
- Numéro de catalogue:CM104043
- Poids moléculaire:279.47
- Point d'ébullition:
- N° Mdl:MFCD11518919
- Stockage:-20°C
Category Infos
- Pyrrolopyrimidines
- Fusion heterocyclic compounds have various biological activities, such as anticancer, antibacterial, antifungal and anti-inflammatory, and thus have been widely used in the field of medicinal chemistry. Pyrrolopyrimidines are a major class of fused heterocyclic compounds. Compared with single pyrrole and pyrimidine cores, pyrrolopyrimidines have more diverse and effective pharmacological characteristics as fusion scaffolds.
Column Infos
- BMF-219
- Biomea Fusion’s BMF-219 demonstrates promising early signs of clinical activity, with its ability to achieve durable and sustained complete responses (CRs) and minimal residual disease negativity (MRD-neg) in patients with acute myeloid leukemia (AML). Biomea Fusion recently presents this First Complete Responder from Ongoing Phase I Study at the 2023 ASH.
BMF-219 is the first and only covalent menin inhibitor in clinical development for AML, ALL, DLBCL, MM and CLL. Additionally, BMF-219 is being explored for its potential to regenerate insulin-producing beta cells as a treatment of type 1 diabetes.