Nom du produit:3-cyclopropylazetidin-3-ol hydrochloride

IUPAC Name:3-cyclopropylazetidin-3-ol hydrochloride

CAS:848192-93-8
Formule moléculaire:C6H12ClNO
Pureté:95%+
Numéro de catalogue:CM108704
Poids moléculaire:149.62

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Détails du produit

N° CAS:848192-93-8
Formule moléculaire:C6H12ClNO
Point de fusion:-
Code SMILES:OC1(C2CC2)CNC1.[H]Cl
Densité:
Numéro de catalogue:CM108704
Poids moléculaire:149.62
Point d'ébullition:
N° Mdl:MFCD13248563
Stockage:

Category Infos

Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

Column Infos

Alicyclic Heterocycles
When the ends of the chains are joined together into a ring, cyclic compounds result; such substances often are referred to as carbocyclic or alicyclic compounds. Substitution of one or more of the ring carbon atoms in the molecules of a carbocyclic compound with a heteroatom gives a heterocyclic compound.