Nom du produit:(R)-O-ISOPROPYLIDENE GLYCEROL MESYLATE
IUPAC Name:[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl methanesulfonate
- CAS：83461-40-9
- Formule moléculaire：C7H14O5S
- Pureté：95%+
- Numéro de catalogue：CM1032311
- Poids moléculaire：210.24
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Détails du produit
- N° CAS:83461-40-9
- Formule moléculaire:C7H14O5S
- Point de fusion:-
- Code SMILES:CC1(OC[C@@H](O1)COS(=O)(=O)C)C
- Densité:
- Numéro de catalogue:CM1032311
- Poids moléculaire:210.24
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- Dioxolanes
- Dioxolane is a heterocyclic acetal with the formula (CH2)2O2CH2. It is related to tetrahydrofuran by exchanging an oxygen for the CH2 group. The isomer 1,2-dioxolane (in which the two oxygen centers are adjacent) is a peroxide. 1,3-Dioxolane is used as solvent and comonomer in polyacetal. The dioxolane-type and their hydrogenolysis can provide very valuable partially protected building blocks either for oligosaccharide syntheses or sugar transformations.
Column Infos
- Mirdametinib
- SpringWorks Therapeutics announced that the Company has initiated a rolling submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for mirdametinib, an investigational MEK inhibitor, in pediatric and adult patients with neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN). The NDA submission includes data from the Phase 2b ReNeu trial. The primary endpoint was confirmed objective response rate (ORR). The BICR-confirmed objective response rate was 52% in pediatric patients and 41% in adult patients. Mirdametinib treatment showed deep and durable responses and demonstrated significant improvements in key secondary patient-reported outcome measures.
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