Nom du produit:2-(4-Chloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
IUPAC Name:2-(4-chloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Product Overview |
2-(4-Chloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, also known as 4-chloro-2-fluoro-1,3-dioxolane, is a synthetic compound. |
Synthesis Method |
The first step involves the reaction of 2-(4-Chloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneluorophenol with sodium borohydride in an aqueous medium. This reaction produces the corresponding boronic acid, which is then reacted with tetramethyl-1,3,2-dioxaborolane in the presence of a base. The reaction yields 2-(4-Chloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneluoro-1,3-dioxolane as the product. |
Physical Properties |
It is a colorless, non-toxic crystalline solid that is soluble in water, alcohols, and other organic solvents. |
Chemical Properties |
It is low toxic, its relatively low cost, and its ease of synthesis. The compound is not very stable and can decompose when exposed to heat or light. |
Synthesis and Application |
It has been used in the synthesis of various compounds such as fluorinated boronic acids, fluorinated arylboronic esters, and fluorinated arylboronic acids. It has also been used in the synthesis of various pharmaceuticals, including some anticonvulsants, antiemetics, and anticonvulsant drugs. Additionally, it has been used in the synthesis of various polymers, such as polysulfone, polyarylate, and polyimide. |