Nom du produit:2-(6-Bromopyridin-2-yl)propan-2-ol
IUPAC Name:2-(6-bromopyridin-2-yl)propan-2-ol
- CAS：638218-78-7
- Formule moléculaire：C8H10BrNO
- Pureté：95%+
- Numéro de catalogue：CM102529
- Poids moléculaire：216.08
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:638218-78-7
- Formule moléculaire:C8H10BrNO
- Point de fusion:-
- Code SMILES:CC(O)(C1=NC(Br)=CC=C1)C
- Densité:
- Numéro de catalogue:CM102529
- Poids moléculaire:216.08
- Point d'ébullition:
- N° Mdl:MFCD16657880
- Stockage:Store at 2-8°C.
Category Infos
- Pyridines
- Pyridine is a six-membered heterocyclic compound containing one nitrogen heteroatom. Pyridine and piperidine are the most frequently occurring heterocyclic building blocks in drug molecules. According to incomplete statistics, there are currently more than 180 drugs containing pyridine or piperidine structure that have been marketed, nearly 1/5 of the drugs approved for marketing in recent years contain these two structures.
- Pyridine | C5H5N | Pyridine Supplier/Distributor/Manufacturer - Chemenu
- Pyridine,Pyridine Wholesale,Pyridine for Sale,Pyridine Supplier,Pyridine Distributor,Pyridine Manufacturer
- Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell.
Column Infos
- Wee1 inhibitors
- Wee1 protein is the most well-known Wee protein, and Wee1 protein kinases are members of the serine/threonine family and are highly conserved in evolution and are abundantly present in many eukaryotes and are very active in the S and G2 phases of the cell cycle. Wee1 protein kinase is a key regulatory center in DNA replication, chromosomal concentration, and histone transcription. These biological behavioral abnormalities can lead to genomic instability and cause malignant tumors, but inhibition or down-regulation of Wee1 protein kinase expression in malignant tumors can trigger mitotic catastrophe and apoptosis leads to tumor cell death. It has now been found that the expression of Wee1 is up-regulated in many cancers, and it has been clinically found that treatment with an inhibitor of Wee1 can effectively improve the occurrence and development of cancer. At present, many companies have deployed this target, and some have progressed to the clinical stage. Some Wee1 inhibitors under development include Adavosertib(ADZ1775), Azenosertib, ZNL-06-096, Debio-0123 and SGR-3515.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.
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