Nom du produit:N-(4-(2-Methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl)acetamide

IUPAC Name:N-(4-{2-methylimidazo[1,2-a]pyridin-3-yl}pyrimidin-2-yl)acetamide

CAS:611239-38-4
Formule moléculaire:C14H13N5O
Pureté:97%
Numéro de catalogue:CM288845
Poids moléculaire:267.29

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Détails du produit

N° CAS:611239-38-4
Formule moléculaire:C14H13N5O
Point de fusion:-
Code SMILES:CC(NC1=NC=CC(C2=C(C)N=C3C=CC=CN32)=N1)=O
Densité:
Numéro de catalogue:CM288845
Poids moléculaire:267.29
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

Imidazopyridines
With four imidazopyridine-containing drugs and one pyrazolopyridine-containing drug on the market, bicyclic pyridines containing ring-junction nitrogen are privileged structures in medicinal chemistry. With two nitrogen atoms with potential to serve as hydrogen bond acceptors, imidazopyridines and pyrazolopyridines may boost binding to target proteins and elevate potency. In addition, these structures have found utility in FBDD, covalent inhibitors, reducing metabolic liabilities, and creating novel chemical space and intellectual properties. With many of the advanced intermediates now commercially available, they will find more and more applications in drug discovery.
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Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

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