Nom du produit:8-chloronaphthalen-1-amine
IUPAC Name:8-chloronaphthalen-1-amine
- CAS:59107-51-6
- Formule moléculaire:C10H8ClN
- Pureté:95%+
- Numéro de catalogue:CM141452
- Poids moléculaire:177.63
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:59107-51-6
- Formule moléculaire:C10H8ClN
- Point de fusion:-
- Code SMILES:ClC1=CC=CC2=CC=CC(N)=C12
- Densité:
- Numéro de catalogue:CM141452
- Poids moléculaire:177.63
- Point d'ébullition:
- N° Mdl:MFCD00465087
- Stockage:Keep in a tight container nitrogen protection,and store at ambient temperature,protect from light
Category Infos
- Naphthalenes
- Naphthalene is a hydrocarbon produced by the distillation of coal tar and is an aromatic white crystalline substance. Naphthalene is the most abundant component in coal tar. It is used as an insect repellant and insect fumigant. The compound is used in the manufacture of celluloid, dyes, hydrogenated naphthalenes, oil fumes, smokeless powders and synthetic resins.
Column Infos
- Adagrasib
- Jan. 10, 2024, EC approves KRAZATI (adagrasib) as a targeted treatment option for patients with advanced non-small cell lung cancer (NSCLC) with a KRAS G12C mutation.
Adagrasib is an orally available, potent, irreversible, small molecule inhibitor of KRAS G12C mutant isoform for the treatment of solid tumours harbouring KRAS G12C oncogenic driver mutation. Adagrasib covalently binds to the mutant cysteine in KRAS G12C and locks the mutant KRAS protein in its inactive state, thereby preventing downstream signalling without affecting wild-type KRAS protein.