cas 57260-71-6|| where to buy N-Boc-piperazine

Nom du produit:N-Boc-piperazine

IUPAC Name:tert-butyl piperazine-1-carboxylate

Unité d'emballage	Stock disponible	Prix($)
CM103943-500g	in stock	Ǌǜ
CM103943-1000g	in stock	ŵƎƎ

Pour une utilisation en R&D uniquement..

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: N° CAS:57260-71-6; Formule moléculaire:C9H18N2O2; Point de fusion:-; Code SMILES:CC(C)(C)OC(=O)N1CCNCC1; Densité:

: Numéro de catalogue:CM103943; Poids moléculaire:186.26; Point d'ébullition:; N° Mdl:MFCD00075265; Stockage:

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: Piperazines; Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.

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: Saruparib; Saruparib, a selective inhibitor of poly-ADP ribose polymerase 1 (PARP1), demonstrated a promising objective response rate and progression-free survival in patients with certain homologous recombination repair (HRR)-deficient breast cancers, according to results from the phase I/II PETRA trial presented at the American Association for Cancer Research (AACR) Annual Meeting 2024.
Saruparib, a PARP1-specific inhibitor, showed promising tumor growth inhibition in preclinical models of breast, ovarian, pancreatic, and prostate cancer harboring HRR deficiency mutations. Because saruparib was less toxic than other PARP inhibitors, it could be given at higher doses.