Nom du produit:3-[(1-hydroxy-2-methylpropan-2-yl)amino]-1lambda6-thiolane-1,1-dione
IUPAC Name:3-[(1-hydroxy-2-methylpropan-2-yl)amino]-1λ⁶-thiolane-1,1-dione
Product Overview |
3-[(1-Hydroxy-2-methylpropan-2-yl)amino]-1lambda6-thiolane-1,1-dione, also known as N-acetylcysteine amide (NACA), is a derivative of N-acetylcysteine (NAC). |
Synthesis Method |
NACA can be synthesized by reacting 3-[(1-Hydroxy-2-methylpropan-2-yl)amino]-1lambda6-thiolane-1,1-dioneeine with isobutyl chloroformate in the presence of triethylamine. The reaction mixture is then treated with thiolane-1,1-dione to yield NACA. |
Chemical Properties |
It is stable and can be easily synthesized in large quantities. It is also relatively non-toxic and has been used in various animal studies without any adverse effects. |
Synthesis and Application |
It has been shown to have antioxidant properties, which protect cells from oxidative stress. NACA has also been found to have anti-inflammatory effects, which make it a potential candidate for the treatment of inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease. Additionally, NACA has been shown to have neuroprotective properties, which make it a potential candidate for the treatment of neurological disorders such as Alzheimer's disease and Parkinson's disease. |
Future Directions |
One area of research is the development of NACA-based therapies for the treatment of various diseases. Another area of research is the elucidation of the mechanism of action of NACA, which will provide insights into its therapeutic potential. Additionally, the development of more potent and selective NACA derivatives may lead to the discovery of novel therapeutic agents. |