cas 54231-35-5|| where to buy 3-Fluoro-2-nitropyridine

Nom du produit:3-Fluoro-2-nitropyridine

IUPAC Name:3-fluoro-2-nitropyridine

Unité d'emballage	Stock disponible	Prix($)
CM103502-100g	in stock	Ǡşş
CM103502-500g	in stock	ƅƻşş
CM103502-1000g	in stock	ƩȋŭǺ

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: N° CAS:54231-35-5; Formule moléculaire:C5H3FN2O2; Point de fusion:-; Code SMILES:O=[N+](C1=NC=CC=C1F)[O-]; Densité:

: Numéro de catalogue:CM103502; Poids moléculaire:142.09; Point d'ébullition:255.8°C at 760 mmHg; N° Mdl:MFCD04114127; Stockage:Keep in a tight container and store at 2°C~8°C

: Pyridines; Pyridine is a six-membered heterocyclic compound containing one nitrogen heteroatom. Pyridine and piperidine are the most frequently occurring heterocyclic building blocks in drug molecules. According to incomplete statistics, there are currently more than 180 drugs containing pyridine or piperidine structure that have been marketed, nearly 1/5 of the drugs approved for marketing in recent years contain these two structures.; Pyridine | C5H5N | Pyridine Supplier/Distributor/Manufacturer - Chemenu; Pyridine,Pyridine Wholesale,Pyridine for Sale,Pyridine Supplier,Pyridine Distributor,Pyridine Manufacturer; Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell.

: Darovasertib; The Journal of Medicinal Chemistry recently publishes an article titled, “Discovery of Darovasertib, a Pan-PKC Inhibitor for the Treatment of Metastatic Uveal Melanoma”. Uveal melanoma (UM) is the most common primary intraocular malignancy. About half of primary uveal melanoma tumors metastasize but with no standard treatment. Most patients with metastatic uveal melanoma have been found to have mutations in GNAQ or GNA11, that are associated with consistent activation of the protein kinase C (PKC) and mitogen-activated protein kinase (MAPK) pathways.
IDEAYA's Darovasertib (IDE196) is a potent, selective small molecule inhibitor of PKC which stops activating PKC/MEK pathway. Darovasertib is under Phase 2 expansion and Phase 3 registrational trial with Crizotinib in GNAQ/11 metastatic cutaneous melanoma.