Nom du produit:N3-Ph-NHS ester

IUPAC Name:2,5-dioxopyrrolidin-1-yl 4-azidobenzoate

CAS:53053-08-0
Formule moléculaire:C11H8N4O4
Pureté:95%+
Numéro de catalogue:CM339184
Poids moléculaire:260.21

Unité d'emballage Stock disponible Prix($) Quantité
CM339184-100mg in stock ǸǙǙ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:53053-08-0
Formule moléculaire:C11H8N4O4
Point de fusion:-
Code SMILES:O=C(ON1C(CCC1=O)=O)C2=CC=C(N=[N+]=[N-])C=C2
Densité:
Numéro de catalogue:CM339184
Poids moléculaire:260.21
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
N-Hydroxysuccinimide (NHS)
N-Hydroxysuccinimide
Azides
Azides are used in click chemistry, such as copper-catalyzed azide-alkyne [3+2] cycloaddition (CuAAC),and strain-promoted [3+2] azide-alkyne cycloaddition reaction (SPAAC).
Non-cleavable linkers
Noncleavable linkers consist of stable bonds that resist proteolytic degradation and provide higher stability than the cleavable linkers.

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