Nom du produit:((1-((6-amino-9H-purin-9-yl)methyl)cyclopropoxy)methyl)phosphonic acid
IUPAC Name:({1-[(6-amino-9H-purin-9-yl)methyl]cyclopropoxy}methyl)phosphonic acid
- CAS：441785-21-3
- Formule moléculaire：C10H14N5O4P
- Pureté：95%
- Numéro de catalogue：CM138508
- Poids moléculaire：299.23
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:441785-21-3
- Formule moléculaire:C10H14N5O4P
- Point de fusion:-
- Code SMILES:NC1=C2N=CN(CC3(OCP(O)(O)=O)CC3)C2=NC=N1
- Densité:
- Numéro de catalogue:CM138508
- Poids moléculaire:299.23
- Point d'ébullition:
- N° Mdl:MFCD09953769
- Stockage:Store at 2-8°C.
Category Infos
- Purines
- Purines are heterocyclic aromatic compounds composed of linked pyrimidine and imidazole rings. In mammals, purines are most commonly expressed in DNA and RNA (including the purines adenine and guanine), as well as single-molecule nucleotides (adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP), cyclic AMP, and to a lesser extent guanosine triphosphate (GTP) and cyclic guanosine monophosphate (cGMP). Purines are also key elements of the following energy metabolism molecules: reduced nicotinamide adenine dinucleotide, nicotinamide adenine dinucleotide phosphate (NADPH), and coenzyme Q. Purines can also act as direct neurotransmitters; for example, adenosine may interact with receptors to modulate cardiovascular and central nervous system (CNS) function.
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- Cyclopropanes
- Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.
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