cas 42754-96-1|| where to buy 4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine

Nom du produit:4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine

IUPAC Name:4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine

Unité d'emballage	Stock disponible	Prix($)
CM104106-5g	in stock	ǟǎ
CM104106-25g	in stock	řŁŁ
CM104106-100g	in stock	ƴřŁ

Pour une utilisation en R&D uniquement..

Formulaire de demande

Nom chimique

Numéro CAS

Quantité*

Spécifications requises*
(% d'analyse, qualité du matériau, etc.)

Nom du contact*

Email du contact*

Notes supplémentaires

Verification code*

refresh

: N° CAS:42754-96-1; Formule moléculaire:C5H2Cl2N4; Point de fusion:-; Code SMILES:ClC1=NC(Cl)=C2C=NNC2=N1; Densité:

: Numéro de catalogue:CM104106; Poids moléculaire:189; Point d'ébullition:; N° Mdl:MFCD09835493; Stockage:Keep in inert atmosphere, store at 2-8°C.

: Pyrazolopyrimidines; Pyrazolopyrimidine scaffolds are one of the most important heterocyclic compounds in drug discovery. This scaffold has various biological activities, among which anticancer is an important one.

: ORIC-533; ORIC-533 is a potential best-in-class, oral inhibitor of CD73 developed by ORIC Pharmaceuticals which is currently in a Ph. Ib trial for the treatment of relapsed/refractory multiple myeloma (MM). It inhibits the CD73-mediated conversion of AMP to adenosine which generates an immunosuppressive tumor microenvironment and has the potential to be a next-generation immunotherapy. The in-depth use of co-crystal structures led the team to discover a novel set of phosphonate bioisosteres which were able to achieve bioavailability for a highly polar scaffold. The structure and discovery story of ORIC-533 were recently presented at the ACS Spring 2024 Meeting in New Orleans.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.