Nom du produit:4-chloro-7H-pyrrolo[2,3-d]pyrimidine
IUPAC Name:4-chloro-7H-pyrrolo[2,3-d]pyrimidine
- CAS:3680-69-1
- Formule moléculaire:C6H4ClN3
- Pureté:95%+
- Numéro de catalogue:CM101908
- Poids moléculaire:153.57
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:3680-69-1
- Formule moléculaire:C6H4ClN3
- Point de fusion:-
- Code SMILES:ClC1=C2C=CNC2=NC=N1
- Densité:
- Numéro de catalogue:CM101908
- Poids moléculaire:153.57
- Point d'ébullition:325.9°C at 760 mmHg
- N° Mdl:MFCD01686865
- Stockage:Keep in a dry and a tight container and store at ambient temperature
Category Infos
- Pyrrolopyrimidines
- Fusion heterocyclic compounds have various biological activities, such as anticancer, antibacterial, antifungal and anti-inflammatory, and thus have been widely used in the field of medicinal chemistry. Pyrrolopyrimidines are a major class of fused heterocyclic compounds. Compared with single pyrrole and pyrimidine cores, pyrrolopyrimidines have more diverse and effective pharmacological characteristics as fusion scaffolds.
Column Infos
- Delgocitinib
- Positive phase 3 head-to-head data results from DELTA FORCE trial comparing delgocitinib cream with alitretinoin capsules in adults with severe chronic hand eczema (CHE). Delgocitinib cream demonstrated a superior reduction in Hand Eczema Severity Index score from baseline to Week 12 compared to alitretinoin capsules as its primary outcome measure.
Delgocitinib cream is an investigational, first-in-class, topical pan-Janus kinase (JAK) inhibitor for CHE. It inhibits the activation of JAK-STAT signaling, which plays a key role in the pathogenesis of CHE.