cas 328962-06-7|| where to buy 4-[1-(4-FLUOROBENZYL)-1H-1,3-BENZIMIDAZOL-2-YL]-1,2,5-OXADIAZOL-3-AMINE

Nom du produit:4-[1-(4-FLUOROBENZYL)-1H-1,3-BENZIMIDAZOL-2-YL]-1,2,5-OXADIAZOL-3-AMINE

IUPAC Name:4-{1-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazol-2-yl}-1,2,5-oxadiazol-3-amine

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: N° CAS:328962-06-7; Formule moléculaire:C16H12FN5O; Point de fusion:-; Code SMILES:NC1=NON=C1C1=NC2=C(C=CC=C2)N1CC1=CC=C(F)C=C1; Densité:

: Numéro de catalogue:CM668721; Poids moléculaire:309.3; Point d'ébullition:; N° Mdl:MFCD01784319; Stockage:

: Benzimidazoles; Benzimidazole is a benzo derivative of imidazole. It is a kind of bicyclic aromatic organic compounds, which is formed by fusing a six-membered benzene ring and five-membered imidazole at positions 4 and 5 of imidazole ring. It is an important pharmacophore of many biologically active heterocyclic compounds with various pharmacological activities. Benzimidazoles and their derivatives have developed into dynamic heterocyclic systems due to their potency in a variety of biologically active compounds such as anticancer, bactericidal and antiviral drugs. Benzimidazoles are a class of therapeutic motifs with broad relevance in medicinal chemistry.

: Furazans; Incorporation of heterocycles into drug molecules can enhance physical properties and biological activity. Oxadiazoles are a class of five-membered heterocycles containing one oxygen and two nitrogen atoms with special biological activity and thermodynamic properties. 1,2,4- and 1,3,4-oxadiazoles are widely used in the development of bioactive molecules, but 1,2,5-oxadiazoles (furazans) are used relatively sparingly. Compared with 1,2,4- and 1,3,4-isomers, 1,2,5-oxadiazole has unique physicochemical properties and electronic effects. The furazan ring has a strong inductive effect, comparable to that of trifluoromethyl or tetrazolyl. The unique properties of furoxan can confer specific pharmacological activities to drug-like molecules.