Nom du produit:1,3-Dihydrospiro[benzo[d]imidazole-2,1'-cyclohexane]

IUPAC Name:1,3-dihydrospiro[1,3-benzodiazole-2,1'-cyclohexane]

CAS:3190-03-2
Formule moléculaire:C12H16N2
Pureté:95%
Numéro de catalogue:CM213815
Poids moléculaire:188.27

Unité d'emballage Stock disponible Prix($) Quantité
CM213815-250mg in stock ŤŮǙ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:3190-03-2
Formule moléculaire:C12H16N2
Point de fusion:-
Code SMILES:C12=CC=CC=C1NC3(CCCCC3)N2
Densité:
Numéro de catalogue:CM213815
Poids moléculaire:188.27
Point d'ébullition:
N° Mdl:MFCD00089091
Stockage:

Category Infos

Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
Spiro And Bicyclic Compound
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Benzimidazoles
Benzimidazole is a benzo derivative of imidazole. It is a kind of bicyclic aromatic organic compounds, which is formed by fusing a six-membered benzene ring and five-membered imidazole at positions 4 and 5 of imidazole ring. It is an important pharmacophore of many biologically active heterocyclic compounds with various pharmacological activities. Benzimidazoles and their derivatives have developed into dynamic heterocyclic systems due to their potency in a variety of biologically active compounds such as anticancer, bactericidal and antiviral drugs. Benzimidazoles are a class of therapeutic motifs with broad relevance in medicinal chemistry.
Cyclohexanes
Cyclohexane is an organic compound with a chemical formula C6H12. It is a colorless liquid with a pungent odor, insoluble in water, and soluble in most organic solvents such as ethanol, ether, benzene, and acetone. Cyclohexyl fragments are a common structure in both natural and synthetic drugs. It can be used as both core structure and part of achiral side chain.