Nom du produit:8-Oxa-2-aza-spiro[4.5]decane

IUPAC Name:8-oxa-2-azaspiro[4.5]decane

CAS:310-93-0
Formule moléculaire:C8H15NO
Pureté:97%
Numéro de catalogue:CM107744
Poids moléculaire:141.21

Unité d'emballage Stock disponible Prix($) Quantité
CM107744-25g in stock ĽNJȎŢ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:310-93-0
Formule moléculaire:C8H15NO
Point de fusion:-
Code SMILES:C1NCCC12CCOCC2
Densité:
Numéro de catalogue:CM107744
Poids moléculaire:141.21
Point d'ébullition:
N° Mdl:MFCD12028170
Stockage:

Category Infos

Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
Spiro And Bicyclic Compound
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Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
Tetrahydropyrans
Tetrahydropyran is an organic compound consisting of a saturated six-membered ring containing five carbon atoms and one oxygen atom. Tetrahydropyrans are common structural motifs in natural products and synthetic therapeutic molecules. In nature, these six-membered oxygen heterocycles are usually assembled by intramolecular reactions, including oxygen Michael addition or ring opening of epoxy alcohols. In fact, polyether natural products have been particularly extensively studied for their fascinating structures and important biological properties; these are often formed through endoselective epoxy open cascades.

Column Infos