Nom du produit:1-(4-bromo-2-methoxy-6-methyl-phenyl)-3-(2-trimethylsilylethoxymethyl)hexahydropyrimidine-2,4-dione
IUPAC Name:1-(4-bromo-2-methoxy-6-methylphenyl)-3-{[2-(trimethylsilyl)ethoxy]methyl}-1,3-diazinane-2,4-dione
- CAS:2940958-65-4
- Formule moléculaire:C18H27BrN2O4Si
- Pureté:95%
- Numéro de catalogue:CM1076998
- Poids moléculaire:443.41
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:2940958-65-4
- Formule moléculaire:C18H27BrN2O4Si
- Point de fusion:-
- Code SMILES:COC1=CC(Br)=CC(C)=C1N1CCC(=O)N(COCC[Si](C)(C)C)C1=O
- Densité:
- Numéro de catalogue:CM1076998
- Poids moléculaire:443.41
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- PROTAC-E3 Ligase Ligands
- Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
- PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.