Nom du produit:1-(4-bromo-2,6-difluoro-phenyl)-3-(2-trimethylsilylethoxymethyl)hexahydropyrimidine-2,4-dione
IUPAC Name:1-(4-bromo-2,6-difluorophenyl)-3-{[2-(trimethylsilyl)ethoxy]methyl}-1,3-diazinane-2,4-dione
- CAS:2940940-46-3
- Formule moléculaire:C16H21BrF2N2O3Si
- Pureté:95%
- Numéro de catalogue:CM1076165
- Poids moléculaire:435.34
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:2940940-46-3
- Formule moléculaire:C16H21BrF2N2O3Si
- Point de fusion:-
- Code SMILES:C[Si](C)(C)CCOCN1C(=O)CCN(C1=O)C1=C(F)C=C(Br)C=C1F
- Densité:
- Numéro de catalogue:CM1076165
- Poids moléculaire:435.34
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- PROTAC-E3 Ligase Ligands
- Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
- PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.