Nom du produit:3-(fluoromethyl)-3-(iodomethyl)oxetane

IUPAC Name:3-(fluoromethyl)-3-(iodomethyl)oxetane

CAS:2940937-63-1
Formule moléculaire:C5H8FIO
Pureté:95%
Numéro de catalogue:CM1077130
Poids moléculaire:230.02

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Détails du produit

N° CAS:2940937-63-1
Formule moléculaire:C5H8FIO
Point de fusion:-
Code SMILES:FCC1(CI)COC1
Densité:
Numéro de catalogue:CM1077130
Poids moléculaire:230.02
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

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