Nom du produit:N-Boc-L-alanine Methyl Ester
IUPAC Name:methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}propanoate
- CAS:28875-17-4
- Formule moléculaire:C9H17NO4
- Pureté:97%
- Numéro de catalogue:CM119523
- Poids moléculaire:203.24
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:28875-17-4
- Formule moléculaire:C9H17NO4
- Point de fusion:-
- Code SMILES:C[C@@H](C(OC)=O)NC(OC(C)(C)C)=O
- Densité:
- Numéro de catalogue:CM119523
- Poids moléculaire:203.24
- Point d'ébullition:
- N° Mdl:MFCD00038513
- Stockage:
Category Infos
- Amino Acids and Peptides
- Amino acids are organic compounds containing a basic amino group and an acidic carboxyl group. Because amino acids contain both amino and carboxyl groups, they can be polymerized in an end-to-end manner, removing a molecule of water to form a covalent amide bond or peptide bond. Many amino acids are linked together end to end to form a polypeptide. Amino acids and peptides are important components in the fields of medicine and life sciences.
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Column Infos
- PF-06648671
- The Journal of Medicinal Chemistry recently publishes an article titled, “Discovery of Clinical Candidate PF-06648671: A Potent γ-Secretase Modulator for the Treatment of Alzheimer’s Disease”. Amyloid β-peptide (Aβ) accumulation is one of the key hallmarks of Alzheimer’s disease (AD). γ-secretase cleaves the amyloid precursor protein (APP) into pathologically relevant Aβs, and has been widely studied as a potential target for the treatment of AD.
Pfizer‘s PF-06648671 is a Gamma secretase modulator (GSM) targeting APP processing. It is found to have excellent central exposure in human and robust reduction of amyloidogenic forms (Aβ42) in cerebrospinal fluid (CSF).