cas 2869955-99-5|| where to buy tert-butyl 4-(1-methoxy-1,3-dioxopentan-2-yl)piperazine-1-carboxylate

Nom du produit:tert-butyl 4-(1-methoxy-1,3-dioxopentan-2-yl)piperazine-1-carboxylate

IUPAC Name:tert-butyl 4-(1-methoxy-1,3-dioxopentan-2-yl)piperazine-1-carboxylate

Unité d'emballage	Stock disponible	Prix($)
CM1078120-100mg	in stock	œŸȤ
CM1078120-500mg	in stock	ǺœşŸ
CM1078120-1g	in stock	ȋşƩœ

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: N° CAS:2869955-99-5; Formule moléculaire:C15H26N2O5; Point de fusion:-; Code SMILES:O=C(OC(C)(C)C)N1CCN(CC1)C(C(=O)OC)C(=O)CC; Densité:1.130±0.06 g/cm3

: Numéro de catalogue:CM1078120; Poids moléculaire:314.38; Point d'ébullition:397.8±42.0 °C; N° Mdl:; Stockage:

: Piperazines; Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.

: HRO761; Novartis'HRO761 is an oral allosteric inhibitor targeting WRN helicase, aimed at treating microsatellite instability (MSI) or deficient mismatch repair (dMMR) tumors. WRN has emerged as a critical synthetic lethal target in MSI cancers, which are common in colorectal, gastric, endometrial, and ovarian cancers. Although MSI cancers show a high response rate to immune checkpoint inhibitors, many patients develop resistance. By acting on WRN, HRO761 may be able to stop the growth of the cancer.
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