Nom du produit:oxetane-2-carboxylic acid methyl ester

IUPAC Name:methyl oxetane-2-carboxylate

CAS:28417-99-4
Formule moléculaire:C5H8O3
Pureté:95%+
Numéro de catalogue:CM464493
Poids moléculaire:116.12

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Détails du produit

N° CAS:28417-99-4
Formule moléculaire:C5H8O3
Point de fusion:-
Code SMILES:COC(=O)C1CCO1
Densité:
Numéro de catalogue:CM464493
Poids moléculaire:116.12
Point d'ébullition:
N° Mdl:MFCD18074101
Stockage:

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

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