Nom du produit:1-(1H-indazol-6-yl)hexahydropyrimidine-2,4-dione

IUPAC Name:1-(1H-indazol-6-yl)-1,3-diazinane-2,4-dione

CAS:2766178-60-1
Formule moléculaire:C11H10N4O2
Pureté:95%
Numéro de catalogue:CM1077309
Poids moléculaire:230.23

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Détails du produit

N° CAS:2766178-60-1
Formule moléculaire:C11H10N4O2
Point de fusion:-
Code SMILES:O=C1CCN(C(=O)N1)C1=CC=C2C=NNC2=C1
Densité:
Numéro de catalogue:CM1077309
Poids moléculaire:230.23
Point d'ébullition:
N° Mdl:
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Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.

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