Nom du produit:N-[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]-9-(hydroxyamino)-9-oxo-nonanamide

IUPAC Name:N'-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]-N-hydroxynonanediamide

CAS:2758388-36-0
Formule moléculaire:C22H28N4O6
Pureté:95%
Numéro de catalogue:CM1077513
Poids moléculaire:444.49

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Détails du produit

N° CAS:2758388-36-0
Formule moléculaire:C22H28N4O6
Point de fusion:-
Code SMILES:ONC(=O)CCCCCCCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1
Densité:
Numéro de catalogue:CM1077513
Poids moléculaire:444.49
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Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.