Nom du produit:5-Bromo-3-(3-((tert-butyldiphenylsilyl)oxy)-2,2-dimethylpropyl)-2-iodo-1H-indole
IUPAC Name:5-bromo-3-{3-[(tert-butyldiphenylsilyl)oxy]-2,2-dimethylpropyl}-2-iodo-1H-indole
- CAS:2641451-43-4
- Formule moléculaire:C29H33BrINOSi
- Pureté:98%
- Numéro de catalogue:CM1069437
- Poids moléculaire:646.48
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:2641451-43-4
- Formule moléculaire:C29H33BrINOSi
- Point de fusion:-
- Code SMILES:IC(N1)=C(CC(C)(C)CO[Si](C2=CC=CC=C2)(C(C)(C)C)C3=CC=CC=C3)C4=C1C=CC(Br)=C4
- Densité:
- Numéro de catalogue:CM1069437
- Poids moléculaire:646.48
- Point d'ébullition:
- N° Mdl:
- Stockage:Keep in dark place,Inert atmosphere,2-8°C.
Category Infos
- Indoles
- Indole is a compound of pyrrole and benzene in parallel, also known as benzopyrrole. There are two combinations of pyrrole and benzene, called indole and isoindole, respectively. Many derivatives of indole have physiological and pharmacological activities, and can synthesize vasodilators, antihistamines, antipyretic analgesics, etc. in medicine, so indole is also a very important heterocyclic compound.
- indole company
- As a indole company,we sincerely welcome the new and old friends from home and abroad to synergize with our company and share the benefits and opportunities.
Column Infos
- RMC-6236
- Over 30% of all human cancers, including a certain percentage of pancreatic, colorectal, lung cancers, and AML are driven by mutations of RAS genes. There is a significant unmet medical need in RAS mutant cancers.
Revolution Medicines’ investigational drug, RMC-6236 is an oral, non-covalent, RAS (ON) inhibitor that is selective for the active, GTP-bound state of both mutant and wild-type variants of the canonical RAS isoforms. RMC-6236 is under clinical phase I studies as monotherapy in NSCLC and PDAC, and advanced solid tumors harboring KRAS G12X mutations.