Nom du produit:2,6-Piperidinedione, 3-(6-fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-

IUPAC Name:3-(6-fluoro-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione

CAS:2468780-87-0
Formule moléculaire:C13H11FN2O3
Pureté:95%+
Numéro de catalogue:CM338820
Poids moléculaire:262.24

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Détails du produit

N° CAS:2468780-87-0
Formule moléculaire:C13H11FN2O3
Point de fusion:-
Code SMILES:O=C(C(N(CC1=C2C=C(F)C=C1)C2=O)CC3)NC3=O
Densité:
Numéro de catalogue:CM338820
Poids moléculaire:262.24
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Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.