Nom du produit:3-(1-oxo-4-prop-2-ynoxy-isoindolin-2-yl)piperidine-2,6-dione

IUPAC Name:3-[1-oxo-4-(prop-2-yn-1-yloxy)-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione

CAS:2434750-54-4
Formule moléculaire:C16H14N2O4
Pureté:95%
Numéro de catalogue:CM1077325
Poids moléculaire:298.3

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Détails du produit

N° CAS:2434750-54-4
Formule moléculaire:C16H14N2O4
Point de fusion:-
Code SMILES:O=C1N(CC2=C(OCC#C)C=CC=C12)C1CCC(=O)NC1=O
Densité:
Numéro de catalogue:CM1077325
Poids moléculaire:298.3
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Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.

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