Nom du produit:3-(1-oxo-4-prop-2-ynoxy-isoindolin-2-yl)piperidine-2,6-dione
IUPAC Name:3-[1-oxo-4-(prop-2-yn-1-yloxy)-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione
- CAS:2434750-54-4
- Formule moléculaire:C16H14N2O4
- Pureté:95%
- Numéro de catalogue:CM1077325
- Poids moléculaire:298.3
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:2434750-54-4
- Formule moléculaire:C16H14N2O4
- Point de fusion:-
- Code SMILES:O=C1N(CC2=C(OCC#C)C=CC=C12)C1CCC(=O)NC1=O
- Densité:
- Numéro de catalogue:CM1077325
- Poids moléculaire:298.3
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- PROTAC-E3 Ligase Ligands
- Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
- PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.