Nom du produit:1-(azetidin-3-yl)-4,4-difluoro-piperidine;dihydrochloride
IUPAC Name:1-(azetidin-3-yl)-4,4-difluoropiperidine hydrochloride
- CAS：2387598-22-1
- Formule moléculaire：C8H15ClF2N2
- Pureté：95%+
- Numéro de catalogue：CM418815
- Poids moléculaire：212.67
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:2387598-22-1
- Formule moléculaire:C8H15ClF2N2
- Point de fusion:-
- Code SMILES:Cl.FC1(F)CCN(CC1)C1CNC1
- Densité:
- Numéro de catalogue:CM418815
- Poids moléculaire:212.67
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- Piperidines
- Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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- Fluorinated Compounds
- Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
- Azetidines
- Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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