Nom du produit:2-cyano-N-[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]acetamide
IUPAC Name:2-cyano-N-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]acetamide
- CAS:2321729-39-7
- Formule moléculaire:C16H14N4O4
- Pureté:95%
- Numéro de catalogue:CM1077280
- Poids moléculaire:326.31
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Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:2321729-39-7
- Formule moléculaire:C16H14N4O4
- Point de fusion:-
- Code SMILES:O=C(CC#N)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1
- Densité:
- Numéro de catalogue:CM1077280
- Poids moléculaire:326.31
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- PROTAC-E3 Ligase Ligands
- Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
- PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.