Nom du produit:(2S,4R)-1-[(2S)-2-[(1-fluorocyclopropanecarbonyl)amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[2-hydroxy-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
IUPAC Name:(2S,4R)-1-[(2S)-2-[(1-fluorocyclopropyl)formamido]-3,3-dimethylbutanoyl]-4-hydroxy-N-{[2-hydroxy-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
- CAS:2306193-99-5
- Formule moléculaire:C26H33FN4O5S
- Pureté:95%+
- Numéro de catalogue:CM340813
- Poids moléculaire:532.63
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:2306193-99-5
- Formule moléculaire:C26H33FN4O5S
- Point de fusion:-
- Code SMILES:O=C([C@H]1N(C([C@@H](NC(C2(F)CC2)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC3=CC=C(C4=C(C)N=CS4)C=C3O
- Densité:
- Numéro de catalogue:CM340813
- Poids moléculaire:532.63
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- PROTAC-E3 Ligase Ligands
- Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
- PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.