Nom du produit:3-(2-fluorophenyl)-1-{5H,6H,7H,8H-imidazo[1,2-a]pyridine-3-carbonyl}azetidine
IUPAC Name:3-(2-fluorophenyl)-1-{5H,6H,7H,8H-imidazo[1,2-a]pyridine-3-carbonyl}azetidine
- CAS：2249165-77-1
- Formule moléculaire：C17H18FN3O
- Pureté：95%+
- Numéro de catalogue：CM1029562
- Poids moléculaire：299.35
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Détails du produit
- N° CAS:2249165-77-1
- Formule moléculaire:C17H18FN3O
- Point de fusion:-
- Code SMILES:FC1=CC=CC=C1C1CN(C1)C(=O)C1=CN=C2CCCCN12
- Densité:
- Numéro de catalogue:CM1029562
- Poids moléculaire:299.35
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- Imidazopyridines
- With four imidazopyridine-containing drugs and one pyrazolopyridine-containing drug on the market, bicyclic pyridines containing ring-junction nitrogen are privileged structures in medicinal chemistry. With two nitrogen atoms with potential to serve as hydrogen bond acceptors, imidazopyridines and pyrazolopyridines may boost binding to target proteins and elevate potency. In addition, these structures have found utility in FBDD, covalent inhibitors, reducing metabolic liabilities, and creating novel chemical space and intellectual properties. With many of the advanced intermediates now commercially available, they will find more and more applications in drug discovery.
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- Azetidines
- Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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