cas 2230803-14-0|| where to buy 3',4'-dihydro-2'H-spiro[oxetane-3,1'-pyrrolo[1,2-a]pyrazine]

Nom du produit:3',4'-dihydro-2'H-spiro[oxetane-3,1'-pyrrolo[1,2-a]pyrazine]

IUPAC Name:3',4'-dihydro-2'H-spiro[oxetane-3,1'-pyrrolo[1,2-a]pyrazine]

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: N° CAS:2230803-14-0; Formule moléculaire:C9H12N2O; Point de fusion:-; Code SMILES:C1OCC11NCCN2C=CC=C12; Densité:

: Numéro de catalogue:CM769681; Poids moléculaire:164.21; Point d'ébullition:; N° Mdl:MFCD31691356; Stockage:

: Oxetanes; Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

: Pyrrolopyrazines; Nitrogen-containing heterocyclic compounds have a wide range of applications in medicine, organic materials, natural products and other fields, mainly for biologically active molecules. Pyrrolopyrazines contain pyrrole and pyrazine rings as bioactive scaffolds. Compounds containing this scaffold have a wide range of biological activities, such as antibacterial, anti-inflammatory, antiviral, antifungal, antioxidant, antitumor, and kinase inhibition.