Nom du produit:Methyl (S)-5-nitro-6-((oxetan-2-ylmethyl)amino)picolinate

IUPAC Name:methyl 5-nitro-6-({[(2S)-oxetan-2-yl]methyl}amino)pyridine-2-carboxylate

CAS:2230200-77-6
Formule moléculaire:C11H13N3O5
Pureté:95%+
Numéro de catalogue:CM1048044
Poids moléculaire:267.24

Unité d'emballage Stock disponible Prix($) Quantité
CM1048044-100mg in stock ǭƩŁ
CM1048044-250mg in stock ƏŁǎ
CM1048044-1g in stock ŽƩǟ

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Détails du produit

N° CAS:2230200-77-6
Formule moléculaire:C11H13N3O5
Point de fusion:-
Code SMILES:O=C(C1=NC(NC[C@H]2OCC2)=C([N+]([O-])=O)C=C1)OC
Densité:
Numéro de catalogue:CM1048044
Poids moléculaire:267.24
Point d'ébullition:491.5±45.0 °C at 760 mmHg
N° Mdl:
Stockage:

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

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