Nom du produit:3-[5-(5-hydroxypent-1-ynyl)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione
IUPAC Name:3-[5-(5-hydroxypent-1-yn-1-yl)-1-oxo-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione
- CAS：2229714-98-9
- Formule moléculaire：C18H18N2O4
- Pureté：95%
- Numéro de catalogue：CM1077491
- Poids moléculaire：326.35
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Détails du produit
- N° CAS:2229714-98-9
- Formule moléculaire:C18H18N2O4
- Point de fusion:-
- Code SMILES:OCCCC#CC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1
- Densité:
- Numéro de catalogue:CM1077491
- Poids moléculaire:326.35
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- PROTAC-E3 Ligase Ligands
- Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
- PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.
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