Nom du produit:6-Chloro-N-cyclopentyl-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

IUPAC Name:[(2R,3R,4R,5R)-3,4-bis(acetyloxy)-5-[6-chloro-4-(cyclopentylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]oxolan-2-yl]methyl acetate

CAS:2226740-87-8
Formule moléculaire:C21H26ClN5O7
Pureté:95%+
Numéro de catalogue:CM1075897
Poids moléculaire:495.92

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CM1075897-1g in stock ƏƅȋƩ

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Détails du produit

N° CAS:2226740-87-8
Formule moléculaire:C21H26ClN5O7
Point de fusion:-
Code SMILES:O(C(C)=O)[C@H]1[C@@H](O[C@H](COC(C)=O)[C@H]1OC(C)=O)N2C=3C(C=N2)=C(NC4CCCC4)N=C(Cl)N3
Densité:
Numéro de catalogue:CM1075897
Poids moléculaire:495.92
Point d'ébullition:
N° Mdl:
Stockage:

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Nucleosides and Nucleotides
Nucleosides consist of a nucleotide and a five-carbon sugar, and a nucleotide consists of a nucleotide, a five-carbon sugar, and one or more phosphate groups.
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ORIC-533
ORIC-533 is a potential best-in-class, oral inhibitor of CD73 developed by ORIC Pharmaceuticals which is currently in a Ph. Ib trial for the treatment of relapsed/refractory multiple myeloma (MM). It inhibits the CD73-mediated conversion of AMP to adenosine which generates an immunosuppressive tumor microenvironment and has the potential to be a next-generation immunotherapy. The in-depth use of co-crystal structures led the team to discover a novel set of phosphonate bioisosteres which were able to achieve bioavailability for a highly polar scaffold. The structure and discovery story of ORIC-533 were recently presented at the ACS Spring 2024 Meeting in New Orleans.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.