Nom du produit:Mal-PEG24-NHS ester

IUPAC Name:

CAS:2226733-37-3
Formule moléculaire:C16H19AN3O8
Pureté:95%+
Numéro de catalogue:CM558848
Poids moléculaire:381

Unité d'emballage Stock disponible Prix($) Quantité
CM558848-100mg in stock ʼnĽǤ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:2226733-37-3
Formule moléculaire:C16H19AN3O8
Point de fusion:-
Code SMILES:O=C(NCCOCCC(ON1C(CCC1=O)=O)=O)CCN2C(C=CC2=O)=O.[24]
Densité:
Numéro de catalogue:CM558848
Poids moléculaire:381
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
Pyrrolines
Pyrrolines, also called dihydropyrroles, are obtained from aromatic pyrroles by hydrogenation. 1-pyrroline is a cyclic imine, while 2-pyrroline and 3-pyrroline are cyclic amines.
ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
Maleimides
Thiol-maleimide is a bifunctional chemical compound that is commonly used in bioconjugation reactions to crosslink two molecules via the thiol (-SH) groups.
N-Hydroxysuccinimide (NHS)
N-Hydroxysuccinimide
Non-cleavable linkers
Noncleavable linkers consist of stable bonds that resist proteolytic degradation and provide higher stability than the cleavable linkers.

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