Nom du produit:(3-cyclopropylfuran-2-yl)boronic acid

IUPAC Name:(3-cyclopropylfuran-2-yl)boronic acid

CAS:2225173-58-8
Formule moléculaire:C7H9BO3
Pureté:95%
Numéro de catalogue:CM326616
Poids moléculaire:151.96

Unité d'emballage Stock disponible Prix($) Quantité

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:2225173-58-8
Formule moléculaire:C7H9BO3
Point de fusion:-
Code SMILES:OB(C1=C(C2CC2)C=CO1)O
Densité:
Numéro de catalogue:CM326616
Poids moléculaire:151.96
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

Furans
Furan is a cyclic flammable liquid compound C4H4O that is obtained from wood oils of pines or made synthetically and is used especially in organic synthesis. Furan is aromatic because a pair of lone pair electrons of the oxygen atom in its molecule forms a large π bond in the plane of the conjugated orbital, making a total of 6 electrons in the plane of the conjugated plane, conforming to the 4n+2 structure. Aromaticity makes furan have the property of easy substitution and difficult addition. The other lone pair of electrons in oxygen stretches out. The oxygen atom itself conforms to sp2 hybridization. Due to the presence of the aromatic ring, the chemical behavior of furan is not very similar to that of other unsaturated heterocycles. The oxygen in the aromatic ring has an electron-donating effect, so the electrophilic substitution reactivity of furan is stronger than that of benzene.
Furan | C4H4O | Where to Buy Furans-Chemenu
Furane | Furanes | Furfuran | Furan | C4H4O | Furan Synthesis | Where to Buy Furans
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Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.