Nom du produit:methyl 3'-oxaspiro[azetidine-3,2'-bicyclo[3.1.0]hexane]-5'-carboxylate trifluoroacetic acid
IUPAC Name:methyl 1-[(2,2,2-trifluoroacetyl)oxy]-3'-oxaspiro[azetidine-3,2'-bicyclo[3.1.0]hexane]-5'-carboxylate
- CAS：2225135-91-9
- Formule moléculaire：C11H12F3NO5
- Pureté：95%+
- Numéro de catalogue：CM479318
- Poids moléculaire：295.21
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:2225135-91-9
- Formule moléculaire:C11H12F3NO5
- Point de fusion:-
- Code SMILES:COC(=O)C12CC1C1(CN(C1)OC(=O)C(F)(F)F)OC2
- Densité:
- Numéro de catalogue:CM479318
- Poids moléculaire:295.21
- Point d'ébullition:
- N° Mdl:MFCD31666385
- Stockage:
Category Infos
- Azetidines
- Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
- Where to buy Azetidines
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- Cyclopropanes
- Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.
- Tetrahydrofurans
- Tetrahydrofuran is a heterocyclic organic compound with the molecular formula C4H8O. Tetrahydrofuran belongs to ethers and is the complete hydrogenation product of furan. It is a colorless, water-miscible organic liquid with small viscosity at normal temperature and pressure. Because of its long liquid range, it is a commonly used medium polar aprotic solvent. Its main use is as a precursor of high molecular polymers.
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